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Re: Introduction to Immunology MBIM 610

David Parker 02 Dec 2011 18:50
in discussion General Discussion / Seminar announcements » Introduction to Immunology MBIM 610

Course Schedule:

• This introductory course will provide students with an overview of how the immune system works and the special vocabulary and experimental systems that describe it.

• We will read and discuss an excellent textbook (Janeway’s Immunobiology) with study questions and occasional experimental papers. There will be a short research proposal and one open book exam at the end of the course.

• The course is designed for two kinds of students:
· Those specializing in other areas who want to learn enough immunology to gain access to the experimental literature.
· Those with a particular interest in immunology. As a 2-credit course, Introduction to Immunology can be fit into the PMCB first year curriculum. This course, or a good undergraduate course in immunology, is a prerequisite for the Advanced Immunology course (MBIM 612, offered in the spring quarter alternate years, next in 2012).

• Introduction to Immunology will be offered every year, with a minimum enrollment of six.

• 2 Credits. One 2 hour class per week. Thursdays 1 to 3.
First meeting Thursday, January 12th, 1 to 3 in RJH 6501. The 8th edition is available in the OHSU bookstore, but it is cheaper at Amazon ($89.91 with free shipping). The e-book version is now available at this link: http://store.vitalsource.com/show/978-1-1366-6521-9. A 6 month e-rental is $62.00. If you are on a tight budget, the 7th edition of the text is adequate for this course.

• Questions? contact
David Parker, course coordinator, <parkerd_at_oshu.edu>, 503 494-1498 or
Ilhem Messaoudi, faculty, <messaoud_at_ohsu.edu>, 503 418-2734

August 4, 2010 David Parker

David Parker 01 Aug 2011 23:41
in discussion General Discussion / Journal Club @ OHSU » August 4, 2010 David Parker

One enduring problem in transplantation immunology is the relative roles of direct (by graft APC) and indirect (by host APC) antigen presentation to the host T cells, further complicated by the ever expanding diversity of APC subsets. In this paper, the authors follow the graft and host APCs and the T cells in vivo in the skin and draining lymph nodes over time during graft rejection by 2 photon microscopy. Is seeing believing? Let's look at the movies, and then you tell me.

If you don't have access to Nature Medicine from this link, here are the pdf files.
http://pig.wikidot.com/local--files/forum:new-thread/Celli%202011.pdf
http://pig.wikidot.com/local--files/forum:new-thread/Celli%202011%20suppl.pdf

—David

51st Midwinter Conference of Immunologists at Asilomar

David Parker 15 Jul 2011 17:55
in discussion General Discussion / News » 51st Midwinter Conference of Immunologists at Asilomar

Conference Website
Conference Schedule

Saturday, January 28
The Dan H. Campbell Memorial Lecturer
Rafi Ahmed

Sunday, January 29
Session I Making and Breaking Tolerance
Diane J. Mathis, Eric Meffre, Ann Marshak-Rothstein, Virginia Pascual
Session II Molecular Mechanisms of Lymphocyte Differentiation
Ann J. Feeney, Amy Weinmann, John J. O'Shea, Ananda A. Goldrath

Monday, January 30
Session III Regulating the Regulators
Luke O"Neill, Dana J. Philpott, Christopher L. Karp, Daniel J. Campbell
Session IV Understanding and Fighting Disease
Louis M. Staudt, Lisa M. Coussens, Karolina A. Palucka, Andrew C-Y Chan

Tuesday, January 31
Session V Response to Invasion
Joanne L. Flynn, Jay K. Kolls, Yasmine Belkaid, Jason G. Cyster

Contract Scientific Review Officers needed at the NIH

David Parker 08 Jul 2011 19:21
in discussion Careers in bioscience / Job postings » Contract Scientific Review Officers needed at the NIH

Here's an email I received from the NIH. If you are interested in this job, let me know and we'll talk about it.
—David Parker
Here's the email from the NIH

Kazuyoshi Kawakami. May 6, 2011. Vollum M1441, 2:00pm

David Parker 15 Apr 2011 18:23
in discussion General Discussion / Seminar announcements » Kazuyoshi Kawakami. May 6, 2011. Vollum M1441, 2:00pm

Friday, May 06, 2011. Visiting Speaker. Vollum M1441, 02:00
Kazuoshi Kawakami, MD/PhD
Professor
Department of Medical Microbiology, Mycology and Immunology
Tohoku University Graduate School of Medicine
"Host defense strategies targeting polysaccharides and glycolipids against Cryptococcus neoformans"
Hosted By: Dr. David Parker

Shannon Turley, Ph.D. Monday, April 25, 2011. 12:00 SEMINAR, Vollum room M1441

David Parker 15 Apr 2011 18:10
in discussion General Discussion / Seminar announcements » Shannon Turley, Ph.D. Monday, April 25, 2011. 12:00 SEMINAR, Vollum room M1441

Visiting Speaker
Monday, April 25, 2011
Shannon Turley, Ph.D.
Associate Professor of Pathology
Dana Farber Cancer Institute & Harvard Medical School
Associate Director, HMS Graduate Program in Immunology
Host: David Lewinsohn, M.D., Ph.D.
12:00 SEMINAR, Vollum room M1441:
The role of lymph node stromal determinants in regulating leukocyte function

2011 Northwest Regional Cytometry Meeting

KSB 23 Feb 2011 19:42
in discussion General Discussion / News » 2011 Northwest Regional Cytometry Meeting

The 2011 Northwest Regional Cytometry Meeting, “Cytometry data: mining, modeling, and management”, will be held March 24 – 26 at OHSU. The meeting will focus on what to do with collected multivariate data, including discussions related to noise, inferring from small numbers, multi-site comparisons, correlative visualization, and automated gating. Confirmed speakers include J. Paul Robinson, Garry Nolan, Norman Dovichi, Manfred Auer, Masanobu Yamamoto, Maria James, Ger van den Engh, Ryan Brinkman, Bob Zigon, C. Bruce Bagwell, and Dave Novo. The NWRCM per se will begin at 3pm on Thursday, March 24, following the FICCS computational cytometry meeting. The Thursday session is followed by an evening reception dinner. The NWRCM continues Friday and Saturday morning. Complimenting the plenaries is a full array of vendor talks, panel discussion on relevant informatic developments, and technical symposia. The full roster and schedule of events is due to be posted soon. Online registration is at http://www.ohsu.edu/ohrc .

In addition to the NWRCM per se, the meeting is an umbrella for a number of other events. Already mentioned is the FICCS computational cytometry meeting on the 24th. Contact Raphael Gottardo or Ryan Brinkman gro.SCCIF|ofnita#gro.SCCIF|ofnita<mailto:[e-mail]> for more information on the FICCS meeting. Also FloCyte will be holding two courses, “Data analysis” on the 24th, and a new one, “Standardization, validation, characterization, and controls” on the 26th, both taught by Dr. Tim Bushnell. A 10% discount is available if also registered for the NWRCM. Finally, a free, half-day cytometry workshop for middle and high school teachers, including lecture and hands-on activities, will be held on the 26th.

Mark your calendars. As always, the NWRCM will be busy, thought-provoking, and useful. If you have any questions, please don’t hesitate to contact the coordinator at ude.usho|emlehcak#ude.usho|emlehcak<mailto:[e-mail]> . Thanks.

Allan Kachelmeier

2011 NWRCM coordinator

Manager, Confocal microscopy core

Oregon Hearing Research Center

OHSU

E. Sally Ward, “Engineering FcRn-IgG interactions for the development of therapeutics”

David Parker 01 Feb 2011 23:18
in discussion General Discussion / Seminar announcements » E. Sally Ward, “Engineering FcRn-IgG interactions for the development of therapeutics”

Visiting Scientist Seminar
“Engineering FcRn-IgG interactions for the development of therapeutics”

presented by

E. Sally Ward, Ph.D.
Paul and Betty Meek – FINA Professorship in Molecular Immunology
Professor, Immunology & Microbiology
UT Southwestern
Graduate School of Biomedical Sciences

Thursday, February 24, 2011
11:00 am
VA Building 101, Room 433

lunch will be served

Sponsored by the Inflammation and Immunology Training Grant

Recent UP graduate seeking research assistant position

Greg Rouse 27 Jan 2011 18:17
in discussion Careers in bioscience / I need a job » Recent UP graduate seeking research assistant position

My name is Greg Rouse. I graduated from the University of Portland in May, 2010. I majored in biology and minored in chemistry, and found a passion for research, specifically in immunology. I am currently volunteering in Dr. William Redmond's lab in the Providence Cancer Center at the Earl A. Chiles Research Institute. I work under general supervision and in coordination with the other lab techs, mainly carrying out Wester Blots. I have also gained experience in preparation of whole cell lysates, Bradford Assays, RNA prep, sterile technique, mouse handling, and tissue sectioning for slides. I have attached my resume below, feel free to contact me with any further questions. My email is ude.pu|01esuor#ude.pu|01esuor.

Thank you for your time and interest,

Greg Rouse

Gregory Michael Rouse
ude.pu|01esuor#ude.pu|01esuor
2001 SE Anderson Ave. Telephone:
Gresham, OR 97080 720-203-2055

Career Goals:
Accomplished research scientist in cancer biology or immunology.

Education:
-B.S. Biology, minor in chemistry, University of Portland May 2010

Laboratory Experience
-University of Portland, Portland, OR 2006-2010
-Effect of retinoic acid on chicken embryo development (Laboratory of Dr. Brown) 2009
-Amplification of Exon 6 of ovine GLB1 gene and comparison to known human mutations (Lab of Dr. Ahern-Rindell) 2009
-Independent research; (Lab of Dr. Hoffman), chemical separation of propolis 2009-2010
-Research Volunteer; Laboratory of Dr. William Redmond, Providence Cancer
Center, Earl A. Chiles Research Institute. Nov 2010-present

Research Techniques:
-DNA extractions -RNA Preparation
-Southern Blot -Protein quantification (Bradford Assay)
-Western Blot -Preparation of whole cell lysates
-Gel Electrophoresis -Infrared Imaging (Li-Cor Odyssey)
-Embryo culture -PCR
-Cell culture -Chromatography

Activities:
-NCAA Division I Men’s Soccer, University of Portland 2006-2010
-University Singers, University of Portland 2008-2010
-Tri-beta Biology Fraternity, University of Portland Chapter 2008-2010

Other Experience:
-Apprentice, Metro Solar Inc. Assisted in manufacturing, installing, replacing,
and servicing solar panels. 2005, 2007
-Painter, University of Portland Physical Plant. Summer, 2008
-Grounds Crew, University of Portland Physical Plant 2009-2010
-Quality Control Technician, Harry’s Fresh Foods Aug, 2010-present

Diane Mathis, March 31st, seminar on Aire

David Parker 11 Jan 2011 20:55
in discussion General Discussion / Seminar announcements » Diane Mathis, March 31st, seminar on Aire

Diane Mathis, Professor of Pathology, Harvard Medical School
Aire control of immunological tolerance: from patients to a molecular mechanism
March 31st, 1 pm, Mac Hall 1162
hosts: James Rosenbaum and David Parker

Treg synapse, MMI Seminar Monday January 10 at 12:00PM in RJH 6524

David Parker 06 Jan 2011 18:02
in discussion General Discussion / Seminar announcements » Treg synapse, MMI Seminar Monday January 10 at 12:00PM in RJH 6524

Please join the department of Molecular Microbiology and Immunology in supporting Tim Thauland, a postdoctoral fellow in the Parker lab who will be presenting "Characterization of the T regulatory cell immunological synapse" on Monday January 10 at 12:00PM in RJH 6524. This seminar will be videoconferenced to the VGTI Library and the Robert P. Franz Conference Room at Providence Medical Center.

Finding OHSU researchers

Robynn Schillace 18 Dec 2010 05:33
in discussion General Discussion / Everything else » Finding OHSU researchers

http://www.ohsu.edu/xd/research/research-expertise/index.cfm

Use this link to find researchers in your area of interest.

Or go to the OHSU home page (ohsu.edu)
select the research tab, then select research expertise (on the left hand side)
Then select explore research at OHSU.

Unfortunately this is limited to OHSU researchers and does not include the VA or providence.

Erin Martin, The Role of B Cell Subsets in Peripheral Tolerance Induction

David Parker 13 Dec 2010 18:40
in discussion General Discussion / Seminar announcements » Erin Martin, The Role of B Cell Subsets in Peripheral Tolerance Induction

The process of central tolerance eliminates self‐reactive B and T lymphocytes as they develop in the bone marrow and thymus. Although stringent, this process is not complete because some auto‐antigens that are not expressed during central tolerance are present in the periphery. Therefore, peripheral tolerance mechanisms are in place to silence any self‐reactive B and T cells that escape central tolerance. New bone marrow B cell emigrants, termed transitional B cells, undergo anergy and eventual apoptosis upon encounter with self‐antigen. Mature T cells may undergo anergy, apoptosis, or develop into regulatory T cells that suppress immune responses. In this study, we examine the role of transitional and mature B cells in T cell tolerance induction. More specifically, we use an in vivo model to provide evidence that transitional and mature follicular B cells are capable of inducing antigen‐specific T cell anergy. Further, we examine the capacity of three B cell subsets in converting naïve T cells to regulatory T cells in vitro. All together, these data implicate B cell subsets in peripheral T cell tolerance induction.

Re: Immunology and Inflammation Retreat - Friday Dec 17

David Parker 01 Dec 2010 23:27
in discussion General Discussion / News » Immunology and Inflammation Retreat - Friday Dec 17

If you have comments on the proposed discussion topics, have a suggestion for another topic, or would like to lead a discussion, please post here.

Immunology and Inflammation Retreat - Friday Dec 17

David Parker 01 Dec 2010 23:20
in discussion General Discussion / News » Immunology and Inflammation Retreat - Friday Dec 17

Inflammation and T Lymphocyte Immunoregulation
1st Annual Retreat
Friday, December 17, 2010
Vey Conference Center, Doernbecher Children's Hospital, OHSU

Talks, Discussion Groups with catered lunch, Poster Session with beer, wine, and snacks.
Everyone is invited. Posters are welcome (see below). Please register now by sending an email to Cindy Morton <mortonc at ohsu.edu>. Indicate whether you will bring a poster or not.

Conference Schedule:

8:30 coffee and tea, plus assorted pastries
9:00 Marielle Gold
9:30 Jeff Gold
10:00 David Parker
10:30 Nancy Haigwood
11:00 Andrew Weinberg
11:30 Discussion Groups with deli lunch (sandwich buffet, salads)
possible topics:
• training in inflammation and immunology research – how are we doing?
• fostering communication, community, and collaboration
• mentoring and career paths for postdocs
• the clinical experience course for graduate students and postdocs
• strategies for managing student debt
1:45 Reports from Discussion Groups
2:15 David Jacoby
2:45 Ilhem Messaoudi
3:15 James Rosenbaum
3:45 Poster Session and Reception (hors d’oeuvres, beer, wine, coffee, tea)

POSTERS:
Easels will be provided but your poster needs to be mounted on a firm backing that should preferably be no larger than 36 x 48 inches.

LOCATION:
We will be meeting in Doernbecher Children’s Hospital on the 11th floor in the Miller Auditorium of the Vey Conference Center click here for maps and directions. If you are entering Doernbecher from the Veteran’s Administration / CDRC side you will take the first elevator you come to up to the 11th floor. If you are entering from OHSU Hospital side you will be on the 9th floor. Go all the way down to the END of the hall following signs to Doernbecher. Pass the first set of elevators along the way (they only go up to the 10th floor) and go all the way to the end of the hall. Take the elevator or stairs up to the 11th floor.

Re: FlowJo Training for Portland

Sachin151 29 Nov 2010 23:28
in discussion General Discussion / News » FlowJo Training for Portland

I would like to attend it.
Thanks
Sachin Puri

Re: FlowJo Training for Portland

mcverweij 29 Nov 2010 21:38
in discussion General Discussion / News » FlowJo Training for Portland

I would like to attend this training. Thanks for organizing!
Marieke Verweij
VGTI/OHSU

Re: FlowJo Training for Portland

Kentaro 29 Nov 2010 20:03
in discussion General Discussion / News » FlowJo Training for Portland

I would like to attend the training.
Thanks.

Kentaro Yomogida
Oregon Health and Science University

Re: FlowJo Training for Portland

erowland 10 Nov 2010 19:04
in discussion General Discussion / News » FlowJo Training for Portland

I would like to attend this training, thank you.
Liz Rowland
OHSU

Philip G Ashton-Rickardt, Ph.D, May 18th at noon

David Parker 10 Nov 2010 18:18
in discussion General Discussion / Seminar announcements » Philip G Ashton-Rickardt, Ph.D, May 18th at noon

“Forward genetic analysis of T lymphocyte immunity to viruses” in the Vollum seminar room at 12:00PM on Wednesday, May 18, 2011.

Dr. Ashton-Rickardt will be speaking about some of the mutants he has identified in an ENU mutagenesis forward genetics program. He has escape mutants that are resistant to immune exhaustion and chronic LCMV infection and mutants with defective memory T cell development.
Dr. Ashton-Rickardt is Professor and Head of the Department of Immunology in the Division of Medicine and Theme Leader in Inflammation and Immunity at Imperial College London, UK. Contact David Parker, host, if you wish to meet with him.

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