Saturday, January 28
The Dan H. Campbell Memorial Lecturer
Rafi Ahmed

Sunday, January 29
Session I Making and Breaking Tolerance
Diane J. Mathis, Eric Meffre, Ann Marshak-Rothstein, Virginia Pascual
Session II Molecular Mechanisms of Lymphocyte Differentiation
Ann J. Feeney, Amy Weinmann, John J. O'Shea, Ananda A. Goldrath

Monday, January 30
Session III Regulating the Regulators
Luke O"Neill, Dana J. Philpott, Christopher L. Karp, Daniel J. Campbell
Session IV Understanding and Fighting Disease
Louis M. Staudt, Lisa M. Coussens, Karolina A. Palucka, Andrew C-Y Chan

Tuesday, January 31
Session V Response to Invasion
Joanne L. Flynn, Jay K. Kolls, Yasmine Belkaid, Jason G. Cyster

In addition to the NWRCM per se, the meeting is an umbrella for a number of other events. Already mentioned is the FICCS computational cytometry meeting on the 24th. Contact Raphael Gottardo or Ryan Brinkman gro.SCCIF|ofnita#gro.SCCIF|ofnita<mailto:info@FICCS.org> for more information on the FICCS meeting. Also FloCyte will be holding two courses, “Data analysis” on the 24th, and a new one, “Standardization, validation, characterization, and controls” on the 26th, both taught by Dr. Tim Bushnell. A 10% discount is available if also registered for the NWRCM. Finally, a free, half-day cytometry workshop for middle and high school teachers, including lecture and hands-on activities, will be held on the 26th.

Mark your calendars. As always, the NWRCM will be busy, thought-provoking, and useful. If you have any questions, please don’t hesitate to contact the coordinator at ude.usho|emlehcak#ude.usho|emlehcak<mailto:kachelme@ohsu.edu> . Thanks.

Allan Kachelmeier

2011 NWRCM coordinator

Manager, Confocal microscopy core

Oregon Hearing Research Center

OHSU

Talks, Discussion Groups with catered lunch, Poster Session with beer, wine, and snacks.
Everyone is invited. Posters are welcome (see below). Please register now by sending an email to Cindy Morton <mortonc at ohsu.edu>. Indicate whether you will bring a poster or not.

Conference Schedule:

8:30 coffee and tea, plus assorted pastries
9:00 Marielle Gold
9:30 Jeff Gold
10:00 David Parker
10:30 Nancy Haigwood
11:00 Andrew Weinberg
11:30 Discussion Groups with deli lunch (sandwich buffet, salads)
possible topics:
• training in inflammation and immunology research – how are we doing?
• fostering communication, community, and collaboration
• mentoring and career paths for postdocs
• the clinical experience course for graduate students and postdocs
• strategies for managing student debt
1:45 Reports from Discussion Groups
2:15 David Jacoby
2:45 Ilhem Messaoudi
3:15 James Rosenbaum
3:45 Poster Session and Reception (hors d’oeuvres, beer, wine, coffee, tea)

POSTERS:
Easels will be provided but your poster needs to be mounted on a firm backing that should preferably be no larger than 36 x 48 inches.

LOCATION:
We will be meeting in Doernbecher Children’s Hospital on the 11th floor in the Miller Auditorium of the Vey Conference Center click here for maps and directions. If you are entering Doernbecher from the Veteran’s Administration / CDRC side you will take the first elevator you come to up to the 11th floor. If you are entering from OHSU Hospital side you will be on the 9th floor. Go all the way down to the END of the hall following signs to Doernbecher. Pass the first set of elevators along the way (they only go up to the 10th floor) and go all the way to the end of the hall. Take the elevator or stairs up to the 11th floor.

PLEASE pass this information along to others at your institution that may have an interest in FlowJo.

This training course will be applicable to users (or potential users) of all skill levels. Instructors will go through basic and advanced data analysis techniques using FlowJo, emphasizing how the software's workflow is intended to accelerate and improve your science. During the second half of the course, instructors will work with data files provided by the students (i.e. bring your data files!) for a first-hand demonstration of the software's capabilities with real-world data.

If you would like to attend, please reply to this posting with your name and institution.

If you have any questions, post them in this forum.

*NOTE: Those of you working at the EACRI can sign up on our internal wiki page and do not need to leave your name here.

See you at the course.

kb

link to the meeting program

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation

Organizers: Bali Pulendran, Rino Rappuoli and Bruce A. Beutler

October 27 - November 1, 2010 • Sheraton Seattle Hotel • Seattle, WA

Meeting Summary

Vaccines have been described as one of the most cost effective public health tools in history. Despite their success, most vaccines have been made empirically, and we understand little about the mechanisms by which they stimulate protective immunity. Indeed, immunologists and vaccinologists have until recently, occupied parallel universes! Understanding the immunology of vaccines and infections is of paramount importance in the rational design of future vaccines against pandemics such as HIV, malaria and tuberculosis, and against emerging infections such as swine influenza and dengue. Recent advances in immunology, human genetics, and systems biology are beginning to offer a deeper understanding of the molecular and cellular mechanisms of host immunity, and the pivotal role played by the innate immune system in shaping the adaptive immune response. Such insights are enhancing our understanding of the correlates of protective immunities, of the early innate immune signatures of vaccine efficacy, and guiding the rational design of novel and safer vaccines and adjuvants. Immunological Mechanisms of Vaccination will bring together an interdisciplinary group of scientists in immunology, virology, systems biology and vaccinology, to address critical advances in these fields and their implications for vaccinology. • The importance of the innate immune system in sensing vaccines and shaping the vaccine immunity • Modulating immune memory to vaccines with innate immunity • Novel approaches to understanding host-pathogen interactions • Deconstructing the mode of action of successful vaccines, vectors adjuvants with innate immunity • Constructing new vaccines and adjuvants with innate immunity • Application of systems biology to predicting vaccine efficacy, and discovering novel immune mechanisms of protection

Don’t miss this exciting Conference to convene at the historic site of Asilomar on the Pacific Coast and the 50th anniversary of the Midwinter Conference of Immunologists! This three-day event is priced less than a bottle of monoclonal antibody! The Registration form on the website (www.midwconfimmunol.org) describes the various housing accommodations and fees for your stay at Asilomar. If you plan to share a room with a registered colleague, please include the name(s) on the form. A spouse or other adult who is not attending the meetings should be registered as a “Guest.” A nominal fee is required and a name badge will be issued for admittance to the Conference receptions. Postdocs, graduate and undergraduate students must present a support letter signed by their sponsor as requested on the form; a group letter will not be accepted.

As an alternative to dining indoors at noontime, choose a To-Go lunch from the dining room; an advanced reservation is not required. A box lunch may be chosen for Tuesday (the last day only) January 25th. Indicate the number of box lunches on the form; please do not exceed the number of persons you have registered.

Registration begins at 3:00 PM, Saturday, January 22nd at the MCI registration area in the front lobby. On Saturday evening at 7.30 PM we will look back at 50 years of MCI, followed by the Dan H. Campbell Memorial Lecture presented by William E. Paul. A reception will follow these presentations in the Nautilus and Triton rooms. The Conference concludes at Noon, Tuesday, January 25th and includes lunch.

Laboratories are urged to develop posters to present at Asilomar. The Poster Sessions are scheduled for Sunday and Monday afternoons and will remain on display for the duration of the Conference. The Poster Abstract form must be downloaded from the website and electronically sent to the address indicated on the form by Friday, December 17, 2010. All posters are accepted and the abstract will allow us to organize them into appropriate groups. Outstanding posters from a postdoctoral fellow and from a graduate student will be selected for the “Ray Owen Young Investigator Award” and for the “Council Award.” In addition, several abstracts will be selected for short talks. Please Note: photographs of poster data and of the slides during the Sessions will not be allowed!

A map of Asilomar and area information is posted at www.asilomarcenter.com. The deadline date for registration without a late fee is Friday, November 19th. The availability of space in January just prior to the meeting may be ascertained from the Registrar preferably by e-mail, ten.uyb|yenrug.mik#ten.uyb|yenrug.mik or telephone 1-650-571-8367 (Eastern Time).

For accommodations after the meeting has convened, call the Asilomar Conference Grounds, 1-831-372-8016, and request to speak with the Registrar, Kim Gurney, at the Midwinter Conference desk.

Visit our website frequently for updated information, www.midwconfimmunol.org. The Conference attendance is limited to 650 attendees and it is suggested that you register as soon as possible.
This exciting Immunology meeting has been planned by the Chairpersons, **Leslie J. Berg and David C. Parker. I look forward to seeing you at Asilomar.

The 50th Midwinter Conference of Immunologists

January 22-25, 2011 Asilomar Conference Grounds, Pacific Grove (near Monterey) California, USA

Schedule of Events - All Sessions in Merrill Hall
Saturday, January 22
3:00 pm Registration begins at Asilomar
7:30 pm 50 years MCI
8:00 pm The Dan H. Campbell Memorial Lecture
9:00 pm Reception Nautilus and Triton Rooms

Sunday, January 23

8:30 - 12:00 Noon Session I
4:00 - 6:00 pm Poster Session Fred Farr Forum and Kiln Rooms
7:30 - 10:00 pm Session II
10:00 - 11:00 pm Reception Fred Farr Forum and Kiln Rooms

Monday, January 24

8:30-12:00 Noon Session III
4:00- 6:00 pm Poster Session Fred Farr Forum and Kiln Rooms
7:30-10:00 pm Session IV
10:00-11:00 pm Reception Fred Farr Forum and Kiln Rooms

Tuesday, January 25

8:30-12:00 Noon Session V
SESSION I:
Sunday Morning 8:00 Noon Speakers
SESSION II:
Sunday Evening 7:30-10:00 pm Speakers
SESSION III:
Monday Morning 8:30 am-Noon Speakers
SESSION IV:
Monday Evening 7:30-10:00 PM Speakers
SESSION V:
Tuesday Morning 8:30 am-Noon Speakers
Chairpersons
Leslie J. Berg and David C. Parker

The Dan H. Campbell Memorial Lecturer

William E. Paul
National Institute of Allergy and Infectious Diseases Bethesda, Maryland

BRIDGING INNATE AND ADAPTIVE IMMUNITY

Chairperson: Jennie P-Y Ting Yong-jun Liu, Max D. Cooper, Bruce Beutler, Jennie P-Y Ting

INTESTINAL COMMENSAL MICROBES: PROTAGONISTS, ANTAGONISTS AND EXTRAS

Chairperson: Eric G. Pamer Richard Blumberg, Dan Littman, David Artis, Eric Pamer

T CELL SIGNALING AND TRANSCRIPTIONAL REGULATION: TUNING THE T CELL RESPONSE

Chairperson: Leslie J. Berg Kris Hogquist, Susan M. Kaech, Ed Palmer, Leslie J. Berg

T CELL RESPONSES TO INFECTION

Chairperson: Michael J. Bevan David G. Brooks, Louis Picker, Richard M. Locksley, Michael J. Bevan

IMMUNOREGULATION AND AUTOIMMUNITY: JUST ENOUGH AND NOT TOO MUCH

Chairperson: David C. Parker Jane H. Buckner, Carola Vinuesa, David C. Parker

~~~This Program will be updated regularly~~~

June 26 - July 1, 2010
University of Pennsylvania, Philadelphia, PA
Course Directors
Terri M. Laufer, M.D.
University of Pennsylvania School of Medicine
and Christopher A. Hunter, Ph.D.
University of Pennsylvania School of Veterinary Medicine

This intensive two-part course, taught by world-renowned immunologists, provides a comprehensive overview of the basics of immunology. This course is for students new to the discipline or those seeking more information to complement general biology or science training.
Part I (June 26 - 28) is a detailed introduction to the basic principles of immunology and is suitable for students with a general biology background. Part II (June 29 – July 1) is a clinically-oriented lecture series.

Online registration closes Friday, June 11.

Advanced Course in Immunology

July 25 - 30, 2010
University of Minnesota, Minneapolis, MN

Course Directors
Yoji Shimizu, Ph.D.
University of Minnesota Center for Immunology
and Stephen C. Jameson, Ph.D.
University of Minnesota Center for Immunology

This intensive course is designed for serious students of immunology. Leading experts will present recent research advances in understanding the biology of the immune system and its role in health and disease.

The course is intended for advanced trainees and scientists who wish to expand or update their understanding of the field. This is not an introductory course; attendees will need to have a firm understanding of the principles of immunology.
Online registration closes Monday, July 12.

Find all the relevant info and registration links via the AAI web site:

http://aai.org/Courses.htm

ABSTRACT: The mechanism by which the immune system produces effector and memory T cells is largely unclear. To allow a large-scale assessment of the development of single naive T cells into different subsets, we have developed a technology that introduces unique genetic tags (barcodes) into naive T cells. By comparing the barcodes present in antigen-specific effector and memory T cell populations in systemic and local infection models, at different anatomical sites, and for TCR–pMHC interactions of different avidities, we demonstrate that under all conditions tested, individual naive T cells yield both effector and memory CD8+ T cell progeny. This indicates that effector and memory fate decisions are not determined by the nature of the priming antigen-presenting cell or the time of T cell priming. Instead, for both low and high avidity T cells, individual naive T cells have multiple fates and can differentiate into effector and memory T cell subsets.

Fierce Biotech article

9:00 – 9:30 - Ashlee Moses (Virology, Vaccine & Gene Therapy Institute)

9:30 – 10:00 - Brian Wong (Microbiology, Infectious Disease)

10:00 – 10:30 - Scott Landfear (Parasitology, Molecular Microbiology & Immunology)

10:30 – 10:45 - COFFE BREAK

10:45 – 11:15 - Bob Searles (Deep Sequencing)

11:15 – 11:45 - Larry David (Proteomics)

11:45 – 12:15 - Stefanie Kaech/Aurelie Snyder (Light Microscopy)

12:15 – 1:15 - LUNCH

1:15 – 2:00 - Poster session

2:00 – 2:30 - Louis Picker (Immunology, Vaccine & Gene Therapy Institute)

2:30 – 3:00 - David Johnson (Virology, Molecular Microbiology & Immunology)

The San Francisco-based company already employs 250 across its local warehouse and packaging lines. As it ramps up biotech manufacturing over the next four years, it expects to add 50 more employees.

On Tuesday Genentech opened its doors to Gov. Ted Kulongoski, the media and other officials to highlight its rapid growth.

Kulongoski aggressively courted the company, and backed a $4.8 million investment in Genentech's move to Oregon. That investment includes a $2 million loan to fund worker training that Genentech will not have to repay because it has already exceeded its job creation target of 200 employees.

"What Genentech brings to us is the opportunity for a seat in a biotechnology sector that will be here for years and years and year," Kulongoski said.

Genentech officials credited Kulongoski and other government officials for their decision to pick Oregon, and said they were also drawn by the state's business climate. Genentech vetted a number of states before ultimately choosing Oregon.
"The tax climate here was very favorable, certainly, when compared to California," said Barry Starkman, manager of the Hillsboro plant.

The company announced its plans to relocate some of its San Francisco manufacturing and distribution to Oregon in 2006. It bought its 75-acre Hillsboro campus that year, and by 2008 had opened its distribution warehouse. It later added a finishing line, where workers oversee an array of machines that lables to drugs made elsewhere, then package the labled drugs for distribution.

Later this month, it will begin manufacturing its first batches of pharmaceuticals, as part of the longer and more thorough process of winning U.S. Food and Drug Administration approval to make and sell drugs commercially.

The company hopes to win approval for its first production line by the first quarter of 2011, and to be making Avastin, Rituxan and Hereptin for domestic and international use by the end of 2013.

Go to the page you want to receive updates from, perhaps the Seminar Announcements section in the Forums.

At the bottom of the page you'll see a section of text that says:

Start watching: site pig.wikidot.com | category forum | this page [?]

• If you click the first choice, site pig.wikidot.com, you'll get an email every time something changes on the PIG site.
• The second selection will alert you any time a change is made in pages of the same category, for example, any addition to any of the forum pages.
• The last selection will alert you to changes on the page you are currently viewing.

You can return to the page and click "Stop watching" at any time to turn this feature off. You can also manage this setting through your account profile.

One more way you can do this - on the Forums page is an option to receive a daily forum digest by email. This way you can get all the forum posts for the day in one easy to digest package.